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Possible link between Crohn's and Parkinson's in Jewish population

Science Daily (US) - 11/01/2018
Researchers have just discovered that patients in the Ashkenazi Jewish population with Crohn's disease (a chronic inflammatory of the digestive system) are more likely to carry the LRRK2 gene mutation. This gene is the major genetic cause of Parkinson's disease, which is a movement disorder.

'Crohn's disease' patient had Heinz sachet in gut

BBC Health News - 03/01/2018
Doctors treating a patient with acute abdominal pain find pieces of sachet in her intestine.

Woman with 'Crohn's' had a Heinz sachet piercing intestine

Daily Mail (UK) - 03/01/2018
The 41-year-old unnamed patient was told she had Crohn's disease. But when she failed to respond to treatment, medics from a Slough hospital carried out keyhole surgery and made the unusual finding.

The little-known symptom of Crohn's disease

Daily Mail (UK) - 02/01/2018
Dr Rishi Goel, a gastroenterologist at Kingston Hospital, London, has revealed the sign isn't listed by NHS Choices - the website designed to give the public information.

Crohn's 'felt like I'd eaten knives'

BBC Health News - 29/12/2017
Chris Barker hasn't let a diagnosis of Crohn's disease stop him from becoming a personal trainer.

International researchers find valuable clues for developing robust therapeutic agents against IBDs

News Medical (Australia) - 26/12/2017
Our immune system protects our bodies from numerous pathogenic microbes and toxins in the environment. The system comprises innate (non-specific) and adaptive (acquired) immunity.

Dysfunctional gene may be cause of Crohn's disease in some patients

News Medical (Australia) - 20/12/2017
This holiday season, millions of people will gather at airports ready to board planes for destinations around the world. Depending on the environment at their destination, their suitcases may be filled with sunscreen and bathing suits, or heavy parkas and mittens.

Dysfunctional gene may be culprit in some Crohn's disease cases

Science Daily (US) - 19/12/2017
Scientists hope that understanding how immune cells adapt as they enter different tissues will spur the design of better, more specific, medicines for Crohn's disease.

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

News Medical (Australia) - 13/12/2017
Inflammatory bowel disease (IBD), including the two conditions ulcerative colitis and Crohn's disease, results in long-term inflammation of the gut and is associated with dysregulation of the immune system.

On tour with Crohn's

BBC Health News - 28/11/2017
What's it like being in a rock band, and dealing with the symptoms of Crohn's disease? Follow Black Foxxes frontman Mark Holley as he pushes himself further than ever.

Engineering the gut microbiome with 'good' bacteria may help treat Crohn's disease

Science Daily (US) - 15/11/2017
Researchers have singled out a bacterial enzyme behind an imbalance in the gut microbiome linked to Crohn's disease. The new study suggests that wiping out a significant portion of the bacteria in the gut microbiome, and then re-introducing a certain type of 'good' bacteria that lacks this enzyme, known as urease, may be an effective approach to better treat these diseases.

Oral bacteria in the gut could drive immune cell induction and inflammatory bowel disease

Science Daily (US) - 14/11/2017
Investigators have investigated the relationship between salivary microbes and IBD, and they found that when the bacterium Klebsiella pneumoniae colonizes in an intestine out of microbial balance, immune cells called T helper 1 (TH1) become overactive in the gut, resulting in intestinal inflammation leading to the onset of IBD.

Inflammatory bowel disease patients over the age of 60 often receive older drugs

News Medical (Australia) - 13/11/2017
Inflammatory bowel disease is common amongst older people and there are big differences in the choice of treatment for different age groups. Patients over the age of 60 often receive cortisone drugs instead of more modern medicines that target the immune system.

X Factor's Lloyd Macey says singing helps Crohn's disease

Daily Mail (UK) - 05/11/2017
The 23-year-old Welshman, who has reached the live finals of this year’s competition, has told of his dramatic six-year battle with Crohn’s.

Smoking cigarettes may cause Crohn's disease

Daily Mail (UK) - 31/10/2017
Scientists at Kyung Hee University, Seoul, discovered mice who inhaled cigarette smoke showed signs of intestinal inflammation - a sign of Crohn's disease.

Celltrion Healthcare announces results from phase III CT-P13 switching trial in patients with Crohn's disease

News Medical (Australia) - 30/10/2017
Today at the 25th United European Gastroenterology Week Congress, Celltrion Healthcare presented data from the phase III, randomized controlled, switching trial comparing CT-P13 and reference infliximab.

IBD: Synthetic hydrogels deliver cells to repair intestinal injuries

Science Daily (US) - 23/10/2017
By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids -- made from human pluripotent stem cells -- researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD).

Increase in inflammatory bowel disease in developing world predicted

Science Daily (US) - 20/10/2017
For the last century, inflammatory bowel disease (IBD) has been a challenge for patients and the medical community in the western world. New research shows that countries outside the western world may now be facing the same pattern of increasing IBD rates.

Study findings provide new insight into inflammatory bowel disease

News Medical (Australia) - 06/10/2017
Findings from a study into Crohn's disease, led by William G. Kerr, Ph.D., of SUNY Upstate Medical University, and his collaborators at the Erasmus Medical Center in the Netherlands, provide the first evidence that patients with debilitating inflammatory bowel disease lack sufficient quantities of a protein that comes from the SHIP1 gene.

Discovery advances understanding of inflammatory bowel disease

Science Daily (US) - 05/10/2017
New findings could help guide doctors to determine how best to treat patients with Crohn's disease, outlines a new report.