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High fat diet reduces gut bacteria, Crohn's disease symptoms

Science Daily (US) - 22/06/2017
A high fat diet may lead to specific changes in gut bacteria that could fight harmful inflammation -- a major discovery for patients suffering from Crohn's disease, research indicates. Crohn's disease, a type of inflammatory bowel syndrome, causes debilitating intestinal swelling, cramping, and diarrhea. The disease affects half a million people in the United States, but its cause is yet unclear.

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

News Medical (Australia) - 22/06/2017
A microscopic fungus called Candida tropicalis triggered gut inflammation and exacerbated symptoms of Crohn's disease, in a recent study conducted at Case Western Reserve University School of Medicine.

Children suffering from IBD not meeting daily recommended intake of calcium and vitamin D

News Medical (Australia) - 29/05/2017
A new study highlights that children suffering from inflammatory bowel disease (IBD) are not meeting the daily recommended intake of calcium and vitamin D. The research, conducted at Great Ormond Street Hospital for Children in London, identified that only 26.6% and 21.3% of paediatric IBD patients were achieving the current recommended intake for calcium and vitamin D respectively.

Cedars-Sinai researchers analyze social media posts to find medication concerns of IBD patients

News Medical (Australia) - 22/05/2017
Cedars-Sinai researchers analyzed thousands of social media posts to determine the biggest concerns patients with inflammatory bowel disease (IBD) have about their prescribed treatments.

Composition, function of intestinal bacteria could predict response to biologic drugs in IBD patients

News Medical (Australia) - 16/05/2017
Analysis of a patient's gut microbiome - the microbial population of the gastrointestinal tract - may be able to predict the likelihood of successful treatment for inflammatory bowel disease with biologic drugs that target immune system activity.

Gut microbiome may predict response to biologic therapy for inflammatory bowel disease

Science Daily (US) - 15/05/2017
Researchers have identified differences in the composition and the function of the gut microbiome between patients for whom treatment with a monclonal antibody-based drug was effective in inducing remission of inflammatory bowel disease symptoms and those for whom it was not.

New ways to detect and monitor inflammatory bowel disease

Science Daily (US) - 15/05/2017
A new test on the mucus lining of the intestine, performed in mice, has found changes in bacteria that could lead to inflammatory bowel disease 12 weeks earlier than previously possible through looking at stool samples, leading to the possibility of earlier diagnosis and better management of the disease in humans.

Key gene is identified in hunt for Crohn's cure

Daily Mail (UK) - 15/05/2017
The prospect of new treatments for incurable bowel disorders has been raised by research identifying a key gene that helps to explain their underlying cause.

Key role for microRNA in inflammatory bowel disease

Science Daily (US) - 09/05/2017
An international team of researchers has discovered that a microRNA produced by certain white blood cells can prevent excessive inflammation in the intestine. The study shows that synthetic versions of this microRNA can reduce intestinal inflammation in mice and suggests a new therapeutic approach to treating patients with Crohn's disease or ulcerative colitis.

What’s the Best Way for Patients with Inflammatory Bowel Disease to Address Abdominal Pain?

Science Daily (US) - 09/05/2017
When researchers analyzed published studies on how to treat recurrent abdominal pain among patients with inflammatory bowel disease, which includes Crohn’s disease and ulcerative colitis, stress management appeared to be a promising strategy.

Eating soy may ease inflammatory bowel disease

Daily Mail (UK) - 02/05/2017
Researchers from Pennsylvania State University have found adding the staple bean to a sufferer's repertoire may improve symptoms of weight loss and an enlarged spleen.

Study shows safety, efficacy of endoscopic needle knife therapy for intestinal strictures in IBD patients

News Medical (Australia) - 28/04/2017
Cleveland Clinic doctors have published the first study illustrating the safety and efficacy of endoscopic needle knife therapy for intestinal strictures in patients with inflammatory bowel disorder.

First endoscopic stricturotomy with needle knife study for intestinal strictures in IBD

Science Daily (US) - 28/04/2017
The first study illustrating the safety and efficacy of endoscopic needle-knife therapy for intestinal strictures in patients with inflammatory bowel disorder has been released by physicians. The results appear to be promising.

Dietary soy-protein may be effective adjunct therapy for inflammatory bowel diseases

News Medical (Australia) - 26/04/2017
A diet supplemented with soy protein may be an effective adjunct therapy for inflammatory bowel diseases, Penn State researchers reported after completing a study that included mice and cultured human colon cells.

Ingesting soy protein may ease severity of inflammatory bowel disease

Science Daily (US) - 26/04/2017
A diet supplemented with soy protein may be an effective adjunct therapy for inflammatory bowel diseases, researchers reported after completing a study that included mice and cultured human colon cells.

Cytokine controls immune cells that trigger inflammatory bowel disease, study finds

Science Daily (US) - 18/04/2017
A certain cytokine, or small protein that helps cells communicate during immune responses, can control whether immune cells promote or suppress inflammatory bowel disease, a finding that could lead to new treatments, according to a study.

Inflammatory bowel diseases on the rise in very young Canadian children

Science Daily (US) - 18/04/2017
Canada has among the highest rates of pediatric inflammatory bowel disease (IBD) in the world, and the number of children under five years old being diagnosed increased by 7.2 percent every year between 1999 to 2010.

New Meds Make Inroads Against Crohn's Disease

MedicineNet (US) - 15/04/2017
Title: New Meds Make Inroads Against Crohn's DiseaseCategory: Health NewsCreated: 4/13/2017 12:00:00 AMLast Editorial Review: 4/14/2017 12:00:00 AM

Genetic link to susceptibility and resistance to inflammatory bowel disease

Science Daily (US) - 13/04/2017
Inflammatory bowel disease (IBD), characterized by chronic relapsing inflammation of the gut, is a common problem in the industrialized world. However, how IBD develops remains unknown. There is currently no cure and treatment options are costly and limited to alleviating symptoms. A new study reveals that the Cd14 gene is a protective factor in experimental inflammatory bowel disease by enhancing the intestinal barrier function.

UC Riverside professor receives grant to explore therapeutic target for treating IBD patients

News Medical (Australia) - 07/04/2017
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis. A protective protein that plays a key role in this disease is "T-cell protein tyrosine phosphatase" or TCPTP.